triclabendazole will improve the amount or impact of modafinil by impacting hepatic enzyme CYP2C19 metabolism.
saquinavir will increase the degree or result of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
For shift perform slumber dysfunction: Older people and teens 17 several years of age and more mature—200 milligrams (mg) one particular hour before you decide to start out Operating. Young people and children younger than seventeen years of age—Use and dose need to be based on your medical doctor. Missed Dose When you miss a dose of this medicine, skip the skipped dose and return to your typical dosing program. Never double doses.
Geriatric Use: In elderly people, modafinil and metabolite elimination is likely to be minimized, so think about using decrease doses and closely keep an eye on people.
Reassess degree of sleepiness commonly; if utilized adjunctively with steady optimistic airway stress (CPAP): Periodic evaluation of CPAP compliance is essential
Hazard of pores and skin reactions (eg SJS, poisonous necrolysis, and drug rash with eosinophilia and systemic symptoms); discontinue if rash or other hypersensitivity reactions take place
The amount of medication that you just take is determined by the toughness from the medicine. Also, the volume of doses you take each day, time permitted in between doses, plus the amount of time you take the drugs count on the medical problem for which you're using the medicine.
Intrauterine growth restriction and spontaneous abortion happen to be reported with modafinil and armodafinil
Keep track of Intently (one)modafinil will raise the amount or impact of diazepam intranasal by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Keep an eye on. Powerful or reasonable CYP2C19 inhibitors may perhaps lower amount of diazepam elimination, thereby rising adverse reactions to diazepam.
cyclophosphamide will enhance the level or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Mysterious.
etravirine will reduce the level or outcome of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Nonetheless, an increased hazard of abortion and intrauterine expansion restriction has become observed in more information certain animal reports. The dangers and great things about therapy all through pregnancy really should be cautiously thought of.[19]
Modafinil is in a class of remedies identified as wakefulness advertising and marketing agents. It really works by transforming the amounts of particular natural substances in the region in the brain that controls slumber and wakefulness.
nevirapine will decrease the level or effect of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.